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Middlesex Commercial Property for Rent

Showing results 1 - 30 of 982

Middlesex, Ontario offers a growing market for commercial properties, perfect for businesses seeking growth opportunities. Explore our extensive listings on Square Yards Canada, featuring over 200 commercial for rent in Middlesex. Each listing includes detailed information about amenities, configurations, and other features about Middlesex commercial for rent. Find the ideal location tailored to your needs, from office spaces and retail stores to industrial units. Utilise our advanced filters to refine your search by area, budget, and property type. Discover top commercial areas like Ajax, Whitby, and Oshawa, and secure the best commercial in Middlesex for rent today.

Last Updated: December 19, 2025

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123 St George Street, Middlesex, ON , MLS #X9348000 , Image - 1

Unit-L15, 123 St George Street East F, London East, Middlesex, ON MLS® X9348000

Commercial (Office)

Price On Request

Very nice professional office space for rent in the downtown core. Professionally managed and occupied by other top quality tenants. 1192 sq ft of spa

8 Photos

390 Hudson Drive, Middlesex, ON , MLS #X11921905 , Image - 1

Unit-Unit 1, 390 Hudson Drive Rural Thames Centre, Thames Centre, Middlesex, ON MLS® X11921905

Commercial (Industrial)

Price On Request

This brand-new facility is designed for transportation, logistics pharmaceutical, life sciences operations, and light manufacturing. It has easy acces

8 Photos

390 Hudson Drive, Middlesex, ON , MLS #X11921906 , Image - 1

390 Hudson Drive Rural Thames Centre, Thames Centre, Middlesex, ON MLS® X11921906

Commercial (Industrial)

Price On Request

This brand-new facility is designed for transportation and logistics operations. It is located 7 minutes from Hwy 401 and 13 minutes from the Hwy 401

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134 Commissioners Road W, Middlesex, ON , MLS #X12639668 , Image - 1

Unit-Upper, 134 Commissioners Road W South O, London South, Middlesex, ON MLS® X12639668

Commercial (Commercial Retail)

$3150.0

Rare leasing opportunity in a prime London location. Situated on a high-traffic main artery, this property boasts exceptional visibility. The unit fea

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564 Newbold Street, Middlesex, ON , MLS #X12248082 , Image - 1

564 Newbold Street South Z, London South, Middlesex, ON MLS® X12248082

Commercial (Industrial)

Price On Request

Professionally managed multi-tenant complex under new ownership. 564 Newbold is 2,400SF (55% Office and 45% warehouse) with 14.9 clear height featuri

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Unit-P3-101, 22499 JEFFERIES Road Kilworth, Middlesex Centre, Middlesex, ON MLS® X8213166

Commercial (Commercial Retail)

Price On Request

1,883 SF is the last unit in building D available at $32.00 psf. Net Rent increases 5% every 2 years. Available on a build-to-suit basis, provided as

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450 Central Avenue, Middlesex, ON , MLS #X12405054 , Image - 1

Unit-409, 450 Central Avenue East F, London East, Middlesex, ON MLS® X12405054

Commercial (Office)

Price On Request

1 Baths

Suite 409 consisting of 851 SF located on the west side of the 4th floor of an established medical-dental building on the north side of Central Ave. b

5 Photos

1464 Beckworth Avenue, Middlesex, ON , MLS #X12126520 , Image - 1

1464 Beckworth Avenue East D, London East, Middlesex, ON MLS® X12126520

Commercial (Commercial Retail)

Price On Request

1 Baths

897 SF inexpensive unit available for lease on ground floor of 3-storey apartment building. CC1 Zoning permits medical-dental offices, financial, pers

5 Photos

30 Pacific Court, Middlesex, ON , MLS #X12126468 , Image - 1

Unit-5, 30 Pacific Court East I, London East, Middlesex, ON MLS® X12126468

Commercial (Industrial)

Price On Request

1 Baths

4,763 SF warehouse with lots of hydro, 14 ft. clear, 2 loading docks, 1washroom, open warehouse, available immediately. Located on north side of Pacif

7 Photos

65 Clarke Road, Middlesex, ON , MLS #X12126486 , Image - 1

Unit-15-17, 65 Clarke Road East P, London East, Middlesex, ON MLS® X12126486

Commercial (Industrial)

Price On Request

2 Baths

4,907 SF (granite business)s available with 30 days notice to existing tenant. Premises can be leased as 1 unit or divided into 2 units (2,388 SF & 2,

4 Photos

520 WELLINGTON Street, Middlesex, ON , MLS #X12126471 , Image - 1

Unit-9, 520 WELLINGTON Street East F, London East, Middlesex, ON MLS® X12126471

Commercial (Office)

Price On Request

2 Baths

Total of 1,603 SF spread over Main floor & lower level. 1,155 SF on main floor with 448 SF in lower level. Retail/Office space in Centennial House (lo

4 Photos

520 WELLINGTON Street, Middlesex, ON , MLS #X12126474 , Image - 1

Unit-5-6, 520 WELLINGTON Street East F, London East, Middlesex, ON MLS® X12126474

Commercial (Commercial Retail)

Price On Request

2 Baths

Total of 3,863 SF spread over Main floor & lower level. 2,372 SF on main floor with 2 areas of 595 SF & 895 SF in lower level. Retail/Office space in

2 Photos

28610 Centre Road, Middlesex, ON , MLS #X12232317 , Image - 1

Unit-D4, 28610 Centre Road NE, Strathroy-Caradoc, Middlesex, ON MLS® X12232317

Commercial (Commercial Retail)

Price On Request

Seize a premier commercial opportunity at Strathroy's gateway! This new development boasts a highly visible location directly off Highway 402, attract

2 Photos

28610 Centre Road, Middlesex, ON , MLS #X12232312 , Image - 1

Unit-D2, 28610 Centre Road NE, Strathroy-Caradoc, Middlesex, ON MLS® X12232312

Commercial (Commercial Retail)

Price On Request

Seize a premier commercial opportunity at Strathroy's gateway! This new development boasts a highly visible location directly off Highway 402, attract

16 Photos

1095 Wilton Grove Road, Middlesex, ON , MLS #X12039957 , Image - 1

1095 Wilton Grove Road South ZZ, London South, Middlesex, ON MLS® X12039957

Commercial (Industrial)

Price On Request

Premier Warehouse/Industrial space available. Easy access and minutes from Highway 401. 49,659 SF available. Additional 7,486 SF of main floor showro

3 Photos

637 Dundas Street E, Middlesex, ON , MLS #X12225113 , Image - 1

Unit-102, 637 Dundas Street E East L, London East, Middlesex, ON MLS® X12225113

Commercial (Commercial Retail)

Price On Request

Prime 850sq ft turn-key-ready unit located along the main corridor on Dundas Street in the vibrant Old East Village. Situated in a highly trafficked a

3 Photos

2070 Huron Street, Middlesex, ON , MLS #X11896981 , Image - 1

2070 Huron Street East E, London East, Middlesex, ON MLS® X11896981

Commercial (Land)

$7000.0

Two acres of fenced and gravelled industrial land available for lease with rare general industrial (GI 1) zoning designation permitting a broad range

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229 Adelaide Street N, Middlesex, ON , MLS #X11909961 , Image - 1

Unit-A, 229 Adelaide Street N East K, London East, Middlesex, ON MLS® X11909961

Commercial (Industrial)

Price On Request

3 Baths

Single use, 16,582 sq ft building on Adelaide at Horton. This building has 4 drive-in doors, dock loading and multiple entrances on Adelaide. Signba

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229 Adelaide Street N, Middlesex, ON , MLS #X11909959 , Image - 1

229 Adelaide Street N East K, London East, Middlesex, ON MLS® X11909959

Commercial (Industrial)

Price On Request

3 Baths

Light Industrial opportunity at Adelaide and Hamilton Road. Two buildings, totaling 24,582 sq ft available for lease. Building A is approximately 16

6 Photos

229 Adelaide Street N, Middlesex, ON , MLS #X11909960 , Image - 1

Unit-B, 229 Adelaide Street N East K, London East, Middlesex, ON MLS® X11909960

Commercial (Industrial)

Price On Request

1 Baths

Fantastic light industrial building available for lease on Adelaide at Horton. This 8000 sq ft building includes 1,476 sq ft of office space. The re

19 Photos

2109 Oxford Street E, Middlesex, ON , MLS #X12630094 , Image - 1

2109 Oxford Street E East I, London East, Middlesex, ON MLS® X12630094

Commercial (Office)

Price On Request

4 Baths

Welcome to 2109 Oxford Street East in London, Ontario. This 9,600 sq. ft. freestanding building sits on a 1.22-acre lot with two floors offers private

8 Photos

3 Buchanan Court, Middlesex, ON , MLS #X12133251 , Image - 1

Unit-2, 3 Buchanan Court South Z, London South, Middlesex, ON MLS® X12133251

Commercial (Industrial)

Price On Request

1 Baths

Prime industrial space with direct Highway 401 exposure is available within a well-maintained, multi-tenant facility in the Westminster Industrial Are

12 Photos

3 Buchanan Court, Middlesex, ON , MLS #X12133269 , Image - 1

Unit-Office, 3 Buchanan Court South Z, London South, Middlesex, ON MLS® X12133269

Commercial (Office)

Price On Request

1 Baths

Prime office space with exceptional Highway 401 exposure is available in a well-maintained, multi-tenant building located in the Westminster Industria

1 Photos

743 Richmond Street East F, London East, Middlesex, ON MLS® X12043412

Commercial (Commercial Retail)

Price On Request

Located at one of the busiest intersections in the area, this prime retail space offers unmatched visibility and exposure for your business. With a st

9 Photos

1305 Commissioners Road E, Middlesex, ON , MLS #X12034459 , Image - 1

Unit-202, 1305 Commissioners Road E South U, London South, Middlesex, ON MLS® X12034459

Commercial (Commercial Retail)

Price On Request

Rare opportunity to Lease space within The ActivityPlex is a One Stop Shop for all a home to best in-class activities including dance, music, indoor p

6 Photos

339 WELLINGTON Road, Middlesex, ON , MLS #X12197308 , Image - 1

Unit-G20A, 339 WELLINGTON Road South G, London South, Middlesex, ON MLS® X12197308

Commercial (Commercial Retail)

Price On Request

Located on the west side just north of Base Line Road in proximity to Victoria Hospital. Mainly medical/dental with some commercial office Tenants. Th

19 Photos

240 Wharncliffe Road N, Middlesex, ON , MLS #X11956335 , Image - 1

Unit-201, 240 Wharncliffe Road N North N, London North, Middlesex, ON MLS® X11956335

Commercial (Office)

Price On Request

Prime Commercial / Professional Office / Medical / Dental Office Building For Lease on Wharncliffe Rd. N. near Oxford St. W., London. Excellent suburb

23 Photos

240 Wharncliffe Road N, Middlesex, ON , MLS #X11956362 , Image - 1

Unit-300, 240 Wharncliffe Road N North N, London North, Middlesex, ON MLS® X11956362

Commercial (Office)

Price On Request

Prime Commercial / Professional Office / Medical / Dental Office Building For Lease on Wharncliffe Rd. N. near Oxford St. W., London. Excellent suburb

8 Photos

240 Wharncliffe Road N, Middlesex, ON , MLS #X11956356 , Image - 1

Unit-300A, 240 Wharncliffe Road N North N, London North, Middlesex, ON MLS® X11956356

Commercial (Office)

Price On Request

Prime Commercial / Professional Office / Medical / Dental Office Building For Lease on Wharncliffe Rd. N. near Oxford St. W., London. Excellent suburb

8 Photos

240 Wharncliffe Road N, Middlesex, ON , MLS #X11956358 , Image - 1

Unit-300B, 240 Wharncliffe Road N North N, London North, Middlesex, ON MLS® X11956358

Commercial (Office)

Price On Request

Prime Commercial / Professional Office / Medical / Dental Office Building For Lease on Wharncliffe Rd. N. near Oxford St. W., London. Excellent suburb

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